David Wolgin
Education
M.A. Vanderbilt; Ph.D. Rutgers; Postdoc Penn, Illinois
Curriculum Vita (pdf.)
Research Interests
Drug tolerance; psychostimulant drugs; basal ganglia; response selection/inhibition
Research Description
Contingent Tolerance to stimulant drugs; role of basal ganglia in inhibiting stimulant-induced stereotypy; recovery from lateral hypothalamic damage.
Recent Publications
Wolgin, D.L. Development and reversal of sensitization to amphetamine-induced hypophagia: Role of temporal, pharmacological, and behavioral variables. Psychopharmacology, 1995, 117, 49-54.
Wolgin, D.L. & Wade, J.V. Learned suppression of stereotypy in amphetamine-treated rats: Implications for understanding tolerance to amphetamine 'anorexia.' Behavioural Pharmacology, 1995, 6, 254-262.
Wolgin, D.L. & Hertz, J.M. Effects of acute and chronic cocaine on milk intake, body weight, and activity in bottle- and cannula-fed rats. Behavioural Pharmacology, 1995, 6, 746-753.
Wolgin, D.L. & Hughes, K.M. Effect of sensitization of stereotypy on the acquisition and retention of tolerance to amphetamine hypophagia. Psychopharmacology, 1996, 126, 219-225.
Wolgin, D.L. & Hughes, K.M. Role of behavioral and pharmacological variables in the loss of tolerance to amphetamine hypophagia. Psychopharmacology, 1997, 132, 342-349.
Hughes, K.M., Popi, L. & Wolgin, D.L. Experiential constraints on the development of tolerance to amphetamine hypophagia following sensitization of stereotypy: Instrumental contingencies regulate the expression of sensitization. Psychopharmacology, 1998, 140, 445-449.
Hughes, K.M., Popi, L. & Wolgin, D.L. Loss of tolerance to amphetamine-induced hypophagia in rats: Homeostatic readjustment versus instrumental learning. Pharmacology Biochemistry & Behavior, 1999, 64, 177-182.
Wolgin, D.L. Contingent tolerance to amphetamine hypophagia: New insights into the role of environmental context in the expression of stereotypy. Neuroscience & Biobehavioral Reviews, 2000, 24, 279-294.
Wolgin, D.L. & Hughes, K.M. Long term retention of tolerance to amphetamine hypophagia following cessation of drug injections and feeding tests. Pharmacology Biochemistry & Behavior, 2001, 70, 367-373.
Wolgin, D.L. Effects of chronic amphetamine on the appetitive and consummatory phases of feeding. Appetite, 2002, 38, 221-223.
Hughes, K.M. & Wolgin, D.L. Changes in behavioral contingencies produce a loss of tolerance to amphetamine hypophagia in rats despite continued tests while drugged. Behavioural Pharmacology, 2002, 13, 279-286.
Wolgin, D.L. & Jakubow, J.J. Tolerance to amphetamine hypophagia: A microstructural analysis of licking behavior in the rat. Behavioral Neuroscience, 2003, 117, 95-104.
Wolgin, D.L. & Jakubow, J.J. Tolerance to amphetamine hypophagia: A real-time depiction of learning to suppress stereotyped movements in the rat. Behavioral Neuroscience, 2004, 118, 470-478.
Wolgin, D.L. & Munoz, J.R. Role of instrumental learning in tolerance to cathinone hypophagia. Behavioral Neuroscience, 2006, 120, 362-370.
Bachand, K.D., Guthrie, K.M. & Wolgin, D.L. Expression of c-fos mRNA in the basal ganglia associated with contingent tolerance to amphetamine-induced hypophagia. Behavioural Brain Research, 2009, 198, 388-396.
Wolgin, D.L. Amphetamine stereotypy, the basal ganglia, and the “selection problem.” Behavioural Brain Research, 2012, 231, 297-308.