Steven Lewis, Ph.D.

Biography

Dr. Lewis received a Ph.D. in physiology from Stanford University (1977). He completed post-doctoral fellowships at University of Copenhagen, Denmark and also in the Division of Cardiology, University of Texas Southwestern Medical School, Dallas. After serving on the Southwestern Medical School faculty from 1981-90, Dr. Lewis, moved to Boston University where he served as a department chair and faculty member and worked extensively in environmental and exercise physiology at the laboratories of the U.S. Army in Natick, MA. Dr. Lewis is internationally known for his research on human muscle fatigue and physical performance in health and disease.

Education

• 1970: B.S., Brooklyn College
• 1971: M.A., Columbia University Teachers College
• 1977: Ph.D., Stanford University

Work History

• 2016-Present: Professor of Integrated Medical Science, Integrated Medical Science Department, Charles E. Schmidt College of Medicine, Florida Atlantic University
• 2014-2016: Visiting Professor of Clinical Biomedical Science, Integrated Medical Science Department, Charles E. Schmidt College of Medicine, Florida Atlantic University
• 2011-2013: Professor of Physiology and Director, Medical Physiology, University of Medicine and Health Sciences-St. Kitts, St. Kitts, WI
• 2009-2010: Professor of Physiology, Department of Neuroscience and Physiology, American University of the Caribbean School of Medicine, St. Maarten, Netherlands Antilles
• 1990-2007: Associate Professor, Department of Health Sciences, Boston University
• 1992-2001: Research Fellow, National Research Council Senior Research Associate and Intergovernmental Personnel Act Assignee, U.S. Army Research Institute of Environmental Medicine, Natick, MA
• 1993: Visiting Professor, Department of Pediatrics, North Shore University Hospital, Cornell University Medical Center
• 1991: Visiting Scientist, Department of Anesthesia, Rigshospitalet, University of Copenhagen, Denmark
• 1990-1992: Chair, Department of Health Sciences, Boston University
• 1990-1992: Visiting Scientist, Clinical Research Center, Massachusetts Institute of Technology, Cambridge, MA
• 1989-1990: Associate Professor, Departments of Physiology and Neurology, University of Texas Southwestern Medical School, Dallas, TX
• 1986-1999: Visiting Scientist and Consultant, Division of Nuclear Medicine, Massachusetts General Hospital, Boston, MA
• 1986-1987: Visiting Professor, Graduate Department of Biochemistry, Brandeis University, Waltham, MA
• 1983-1989: Assistant Professor, Department of Physiology, University of Texas Southwestern Medical School Dallas, TX
• 1981-1983: Instructor, Department of Physiology, University of Texas Southwestern Medical School, Dallas, TX
• 1978-1990: Visiting Scientist, Department of Clinical Physiology, Linköping University Hospital, Linköping, Sweden

Scholarly Activity

Research Interests

• Human muscle fatigue and factors affecting physical performance in health and disease
• Health benefits of exercise and regular physical activity

Research funding

• Research Funding: SF Lewis, Principal Investigator “Cardiovascular Control and Chronic Adaptations to Exercise in Disorders of Muscle Energy Metabolism”; NIH Program Project section (with NIH RO1 simultaneously approved); 1987-92; $495,055.
• “Muscle Metabolism and Circulatory Control in Exercise”; NIH Research Career Development Award; 1986-90; $248,067.
• “Ventilatory Control During Exercise in Muscle Disease”; American Heart Association (National Center) Grant-In-Aid; 1983-86; $96,000.
• “Exercise Circulatory Control in Neuromuscular Disease”; NIH New Investigator Research Award; 1981-84; $103,203.

Peer-Reviewed Publications

• Lewis, SF, CH Hennekens. Regular physical activity: forgotten benefits. Am J Med published online ahead of print, Aug 2, 2015.
• Lewis SF, S Vora, RG Haller. Abnormal oxidative metabolism and O2 transport in muscle phosphofructokinase deficiency. J Appl Physiol 70:391-398, 1991.
• Haller RG, SF Lewis. Glucose-induced exertional fatigue in muscle phosphofructokinase deficiency N Eng J Med 324:364-369, 1991.
• Haller RG, KG Henriksson, L Jorfeldt, E Hultman, R Wibom, K Sahlin, N-H Areskog, M Gunder, K Ayyad, CG Blomqvist, RE Hall, P Thullier, NG Kennaway, SF Lewis. Deficiency of muscle succinate dehydrogenase and aconitase: pathophysiology of exercise in a novel human muscle oxidative defect. J Clin Invest 88:1197-1206, 1991.
• Lewis SF, RG Haller. Physiological measurement in exercise and fatigue with special reference to chronic fatigue syndrome. Rev Infect Dis 13(Suppl 1):S98-S108, 1991.
• Katz A, MK Spencer, S Lilloija, Z Yan, DM Mott, RG Haller, SF Lewis. Carbohydrate metabolism in human skeletal muscle deficient in phosphofructokinase-1: normal and aberrant responses to insulin. Am J Physiol 261:E437-E443, 1991.
• Pryor SL, SF Lewis, RG Haller, LA Bertocci, RG Victor. Impairment of sympathetic nerve activity during static exercise in patients with muscle phosphorylase deficiency (McArdle's disease). J Clin Invest 85:1444-1449, 1990.
• Lewis SF, RG Haller. Skeletal muscle disorders and associated factors that limit exercise performance. IN: Exercise and Sport Sciences Reviews, Vol 17 (ed) K.B. Pandolf, Williams and Wilkins, Baltimore, pp. 67-113, 1989.
• Haller RG, SF Lewis, RW Estabrook, S DiMauro, S Servidei, DW Foster. Exercise intolerance, lactic acidosis and abnormal cardiopulmonary regulation in exercise associated with adult skeletal muscle cytochrome c oxidase deficiency. J Clin Invest 84:155-161, 1989.
• Lewis SF, RG Haller. The pathophysiology of McArdle's disease: clues to regulation in exercise and fatigue. J Appl Physiol 61:391-401, 1986.

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Teaching Interests

• Cardiovascular physiology
• Pulmonary physiology
• Nutritional physiology
• Pharmacodynamics and pharmacokinetics
• Autonomic nervous system physiology and pharmacology

Honors

• 1986: American Heart Association Established Investigator Award Finalist
• 1985: American Heart Association Established Investigator Award Finalist

Present/Past Editorial Board Memberships

Journal of Musculoskeletal Pain, Journal of Cancer Studies and Therapy, Medicine and Science in Exercise and Sports

Other Work

• 1992: NIH Special Study Section Member
• More than 40 invited lectures: national and international

Awards

• 1996-97: National Research Council Senior Research Associateship
• 1986-90: NIH Research Career Development Award
• 1983: American Physiological Society Travel Award
• 1981-84: NIH New Investigator Research Award
• 1980: American College of Sports Medicine New Investigator Award
• 1977-78: George C. Marshall Fellowship

Memberships

• Fellow and Past Member of Board of Trustees, American College of Sports Medicine
• Member, American Physiologial Society