2023 Publications


Optical Imaging Reveals Liver Metabolic Perturbations in Mblac1 Knockout Mice.
Ceyhan B, LaMar J, Nategh P, Neghabi M, Konjalwar S, Rodriguez P, Hahn MK, Blakely RD, Ranji M.
Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-4. doi: 10.1109/EMBC40787.2023.10341032.
PMID: 38083729


Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease.
Mayer FP, Stewart A, Blakely RD.
Basic Clin Pharmacol Toxicol. 2024 Feb;134(2):206-218. doi: 10.1111/bcpt.13964. Epub 2023 Dec 6.
PMID: 37987120


Sink or swim: Does a worm paralysis phenotype hold clues to neurodegenerative disease?
Rodriguez P, Blakely RD.
J Cell Physiol. 2024 Jun;239(6):e31125. doi: 10.1002/jcp.31125. Epub 2023 Oct 5.
PMID: 37795580


Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Luis TC, Barkas N, Carrelha J, Giustacchini A, Mazzi S, Norfo R, Wu B, Aliouat A, Guerrero JA, Rodriguez-Meira A, Bouriez-Jones T, Macaulay IC, Jasztal M, Zhu G, Ni H, Robson MJ, Blakely RD, Mead AJ, Nerlov C, Ghevaert C, Jacobsen
SEW.Nat Commun. 2023 Sep 28;14(1):6062. doi: 10.1038/s41467-023-41691-y.
PMID: 37770432


Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells.
Haque TT, Taruselli MT, Kee SA, Dailey JM, Pondicherry N, Gajewski-Kurdziel PA, Zellner MP, Stephenson DJ, MacKnight HP, Straus DB, Kankaria R, Jackson KG, Chumanevich AP, Fukuoka Y, Schwartz LB, Blakely RD, Oskeritzian CA, Chalfant CE, Martin RK, Ryan JJ.
Sci Signal. 2023 Sep 12;16(802):eabc9089. doi: 10.1126/scisignal.abc9089. Epub 2023 Sep 12.
PMID: 37699080


Disruptive mutations in the serotonin transporter associate serotonin dysfunction with treatment-resistant affective disorder.
Støier JF, Jørgensen TN, Sparsø T, Rasmussen HB, Kumar V, Newman AH, Blakely RD, Werge T, Gether U, Herborg F.
medRxiv. 2023 Aug 29:2023.08.29.23294386. doi: 10.1101/2023.08.29.23294386. Preprint.
PMID: 37693601 Free PMC article.


Divergent Actions of Renal Tubular and Endothelial Type 1 IL-1 Receptor Signaling in Toxin-Induced AKI.
Ren J, Liu K, Wu B, Lu X, Sun L, Privratsky JR, Xing C, Robson MJ, Mao H, Blakely RD, Abe K, Souma T, Crowley SD.
J Am Soc Nephrol. 2023 Aug 7. doi: 10.1681/ASN.0000000000000191. Online ahead of print.
PMID: 37545036


Kappa Opioid Receptor Antagonism Rescues Genetic Perturbation of Dopamine Homeostasis: Molecular, Physiological and Behavioral Consequences.
Mayer FP, Stewart A, Varman DR, Moritz AE, Foster JD, Owens AW, Areal LB, Gowrishankar R, Velez M, Wickham K, Phelps H, Katamish R, Rabil M, Jayanthi LD, Vaughan RA, Daws LC, Blakely RD, Ramamoorthy S.
bioRxiv. 2023 May 3:2023.05.03.539310. doi: 10.1101/2023.05.03.539310. Preprint.
PMID: 37205452


Serotonin in the orbitofrontal cortex enhances cognitive flexibility.
Hyun JH, Hannan P, Iwamoto H, Blakely RD, Kwon HB.
bioRxiv. 2023 Mar 9:2023.03.09.531880. doi: 10.1101/2023.03.09.531880. Preprint.
PMID: 36945634


Serotonin-releasing agents with reduced off-target effects.
Mayer FP, Niello M, Cintulova D, Sideromenos S, Maier J, Li Y, Bulling S, Kudlacek O, Schicker K, Iwamoto H, Deng F, Wan J, Holy M, Katamish R, Sandtner W, Li Y, Pollak DD, Blakely RD, Mihovilovic MD, Baumann MH, Sitte HH.
Mol Psychiatry. 2023 Feb;28(2):722-732. doi: 10.1038/s41380-022-01843-w. Epub 2022 Nov 9.
PMID: 36352123