2016 Publications
Nackenoff AG, Moussa-Tooks AB, McMeekin AM, Veenstra-VanderWeele J, Blakely RD. Essential Contributions of Serotonin Transporter Inhibition to the Acute and Chronic Actions of Fluoxetine and Citalopram in the SERT Met172 Mouse. Neuropsychopharmacology. 2016 Jun;41(7):1733-41. doi: 10.1038/npp.2015.335. Epub 2015 Oct 30. PMID: 26514584; PubCentral PMCID: PMC4869040.
Margolis KG, Li Z, Stevanovic K, Saurman V, Israelyan N, Anderson GM, Snyder I, Veenstra-VanderWeele J, Blakely RD, Gershon MD. Serotonin transporter variant drives preventable gastrointestinal abnormalities in development and function. J Clin Invest. 2016 Jun 1;126(6):2221-35. doi: 10.1172/JCI84877. Epub 2016 Apr 25. PMID: 27111230
Ennis EA, Blakely RD. Choline on the Move: Perspectives on the Molecular Physiology and Pharmacology of the Presynaptic Choline Transporter. Adv Pharmacol. 2016;76:175-213. doi: 10.1016/bs.apha.2016.03.001. Epub 2016 Apr 7. PMID: 27288078
Iwamoto H, Calcutta MW, Blakely RD. Differential impact of genetically modulated choline transporter expression on the release of endogenous versus newly synthesized acetylcholine. Neurochem Int. 2016 Mar 22. pii: S0197-0186(16)30038-9. doi: 10.1016/j.neuint.2016.03.012. [Epub ahead of print] PMID: 27013347
Robson MJ, Zhu CB, Quinlan MA, Botschner DA, Baganz NL, Lindler KM, Thome JG, Hewlett WA, Blakely RD. Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1. PLoS One. 2016 Mar 1;11(3):e0150068. doi: 10.1371/journal.pone.0150068. eCollection 2016. PubMed PMID: 26930558; PubMed Central PMCID: PMC4773179.
Bermingham DP, Hardaway JA, Snarrenberg CL, Robinson SB, Folkes OM, Salimando GJ, Jinnah H, Blakely RD. Acute blockade of the Caenorhabditis elegans dopamine transporter DAT-1 by the mammalian norepinephrine transporter inhibitor nisoxetine reveals the influence of genetic modifications of dopamine signaling in vivo. Neurochem Int. 2016 Feb 3. pii: S0197 0186(16)30008-0. doi: 10.1016/j.neuint.2016.01.008. [Epub ahead of print] PubMed PMID: 26850478.
Ye R, Quinlan MA, Iwamoto H, Wu HH, Green NH, Jetter CS, McMahon DG, Veestra-VanderWeele J, Levitt P, Blakely RD. Physical Interactions and Functional Relationships of Neuroligin 2 and Midbrain Serotonin Transporters. Front Synaptic Neurosci. 2016 Jan 11;7:20. doi: 10.3389/fnsyn.2015.00020. eCollection 2015. PubMed PMID: 26793096; PubMed Central PMCID: PMC4707279.
Sarter, M., Lustig, C., Blakely, R.D., Koshy Cherian, A. Cholinergic genetics of visual state attention: human and mouse choline transporter variants influence distractibility, J. Physiol Paris. 110:10-18, 2016. [PMID: 27404793; PMCID: In Progress]
Ennis, E.A. and Blakely, R.D., Choline on the move: Perspectives on the physiology and pharmacology of the presynaptic choline transporter, Adv Pharmacol 176:175-213, 2016. [PMID: 27288078, PMCID: In Progress]
Bermingham, D.P. and Blakely, R.D., Kinase-dependent regulation of monoamine neurotransmitter transporter regulation, Pharmacological Reviews, 68:888-953, 2016. [PMID: 27591044, PMCID: In Progress]
Brindley, R. L., Bauer, M.B., Blakely, R.D., and Currie, K.P.M. An interplay between the serotonin transporter (SERT) and 5-HT receptors controls stimulus secretion coupling in sympathoadrenal chromaffin cells, Neuropharmacology, 110, 438-448, 2016. [PMID: 27544824: PMCID: IN Progress]
Bertron, J.L., Ennis, E.A., Tarr, C.J., Dickerson, J.W., Wright, J., Locuson, C.W., Blobaum, A.L. Rook, J.M., Blakely, R.D., and Lindsley, C.W. Optimization of the choline transporter (CHT) inhibitor ML352: Development of VU6001221, an improved in vivo tool compound, Biorg and Med Chem Letters, 4637-4640, 2016. [PMID: 27575469; PMCID:IN Progress].
Robinson, S.B., Hardaway, J.A., Hardie, S.L., Wright, J., Glynn, R.M., Sturgeon, S.M., Freeman, P., Blakely, R.D., Sequence determunants of the C. elegans dopamine transporter dictating in vivo axonal export and synaptic localization, Mol Cell Neurosci, 78:41-51, 2016. [PMID: 27913309; PMCID: In Progress]