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E. Schmidt College of Medicine
Link to
Charles E. Schmidt College of Medicine Programs
Undergraduate Courses
Brain Diseases: Mechanism and Therapy (BMS
4732) 3 credits
Prerequisite: Permission of instructor
Course includes discussion of the molecular and cellular basis of brain diseases
and provides the current status of therapeutic intervention for brain diseases.
Introduction to Radiation Biology (BSC
4833) 3 credits
Prerequisites: BSC 1010, PHY 2048,
PHY 2049 and permission of instructor
An overview of the effects of ionizing radiation on humans and other biological
systems. It involves consideration of cell survival after exposure to ionizing
radiations, repair of radiation damage, radiosensitizers, radioprotectors,
doses and risks in diagnostic radiology, cardiology and nuclear medicine, and
basic safety rules.
Introduction to Preprofessional Studies
(PCB 3083) 3 credits
Prerequisites: 8 credits general chemistry,
8 credits general biology, permission of instructor; Corequisite:
PCB 3083L
To familiarize premedical or allied field students with the requirements, demands
and rewards of a career in medicine. The course features lectures about a variety
of medical disciplines.
Introduction to Preprofessional Studies
Lab (PCB 3083L) 1 credit
Prerequisite: Permission of instructor;
Corequisite: PCB 3083
Shadowing of physicians in hospital and office settings, including visits to
local facilities and observations of actual medical procedures. Grading: Pass/fail
option.
RNA Biology and Diseases (PCB 4521) 3 credits
Prerequisite: Permission of instructor
This course provides advanced-level training in molecular biology of RNA. It
covers the fundamental principles of RNA structure, function and metabolism;
methodologies for studying RNA; diseases related to RNA deficiencies; and applications
of RNA technologies in research and clinical development.
Reproductive Endocrinology (PCB 4803) 3
credits
Prerequisites: BSC 1010, 1010L, 1011,
1011L; CHM 2045, 2045L, 2046, 2046L;
and permission of instructor
Course describes the origin, structure, properties and physiological actions
of hormones related to reproductive function, as well as the clinical implications
of their deficiency and excess at different stages of life. The anatomy, histology
and physiology of reproductive organs and related endocrine glands are studied.
This course is taught in a case-based manner. Participation in seminars presented
by graduate students on topics related to the lectures is required at the end
of the course.
Directed Independent Study (PCB 4905) 1-3
credits
Prerequisite: Permission of instructor
and department
Independent research.

Special Topics (PCB 4930) 1-8 credits
Special topics of interest to biomedical students.
Graduate Courses
Integrated Morphology
1 (BMS 6102C) 4 credits
Prerequisite: Permission of
instructor
This course involves the developmental,
microscopic and gross anatomical features of the organs located
in the thorax and abdomen of the human. A laboratory includes
a cadaveric dissection experience and examination of tissue samples
using virtual microscopy.
Integrated Morphology 2 (BMS 6104C) 4 credits
Prerequisite: Permission of
instructor
This course involves the gross anatomical
features of the structures of the back, limbs, head and neck
of the human. A laboratory includes a cadaveric dissection experience.
Autonomic Function and Diseases (BMS 6523) 3 credits
Prerequisite: Permission of instructor
Course covers both the physiological and clinical study of the autonomic nervous
system (ANS) emphasizing the neural circuitry aspects of systemic regulation.
Topics are introduced in lectures and followed up by recent journal articles.
Fundamentals of General Pathology (BMS 6601) 2
credits
Covers the basic pathophysiology of mechanisms of disease in medicine and incorporates
gross pathologic, microscopic and radiologic material to assist in understanding
fundamental disease.
Brain Diseases: Mechanism and Therapy (BMS
6736) 3 credits
Prerequisite: Permission of instructor
Discussion of the molecular and cellular basis of brain diseases and of the
current status of therapeutic intervention for those diseases.

Introduction to Radiation Biology (BSC
6834) 3 credits
Prerequisites: BSC 1010, 1010L, PHY
2048, 2048L, 2049, 2049L and
permission of instructor
An overview of the effects of ionizing radiations on human and other biological
systems. The course involves consideration of cell survival after exposure
to ionizing radiations, repair of radiation damage, radiosensitizers and radioprotectors,
doses and risks in diagnostic radiology, cardiology, nuclear medicine, and
basic safety rules. A student seminar is required at the end of the course.
Molecular Genetics of the Cell (GMS 6220) 3 credits
Prerequisite: BCH 3033 or PCB 3063 or equivalent
Provides a basic background in cell and molecular biology. Emphasis on human
physiology and disease.
Macromolecules and Human Disease (GMS 6301) 3
credits
Prerequisite: BCH 3033 or PCB 4023 or
equivalent
Explores structure and function of biological macromolecules with emphasis
on DNA, RNA and proteins.
Molecular Basis of Disease and Therapy
(GMS 6302) 3 credits
Prerequisites: BCH 4035 and (PCB 4023
or PCB 4522)
Explores the molecular basis of selected viral pathogens, genetic diseases
and cancer through lectures and presentations by faculty in the College of
Science and College of Medicine, Scripps Florida and private industry representatives.
Discusses novel technologies aimed at developing therapeutics together with
the activity of modern biotechnology in drug development.
Molecular Neuropsychopharmacology (GMS 6735) 3 credits
Prerequisite: PSB 6037 or PSB 6345 or equivalent
Provides the fundamentals of molecular neuropharmacology as they relate to
neurotransmitter signaling in the brain.
Host Defense and Inflammation (MCB 6208) 3 credits
Prerequisite: PCB 4233 or equivalent with a minimum
grade of "B-"
Course covers the immunology emphasizing mechanisms of host defense and inflammation
in chronic inflammatory diseases. Mechanisms emphasized are roles of macrophages
that are heterogeneous and diverse populations regulating host defense and
inflammation. Mycobacterial infections and allergic asthma are presented as
disease models of chronic inflammatory diseases.
Advanced Cell Physiology (PCB 6207) 3 credits
Prerequisite: Permission of instructor
Course describes in-depth membrane physiology, intracellular signaling pathways
and cellular function, with an emphasis on neurons and human muscle cells (skeletal,
smooth and cardiac muscle cells).
Molecular Basis of Human Cancer (PCB 6235) 3 credits
Prerequisites: Graduate standing and PCB 4023
or BCH 3033 or PCB 6207 with minimum grade of "B-"
Course covers current concepts and knowledge of cancer, exploring the molecular
and cellular mechanisms underlying cancer progression with an aim to understand
the processes of tumorigenesis.

Problem-Based Immunology (PCB 6238) 3 credits
Prerequisites: Graduate standing and PCB 4233 or
equivalent with a minimum grade of "B-"
Course provides an up-to-date understanding of the basic science of immunology
and how that science applies to the realities of patient care. The fundamental
mechanisms of immunity are illustrated by autoimmune and alloimmune diseases.
Tumor Immunology (PCB 6239) 3 credits
Prerequisites: Graduate standing and PCB 4233
or equivalent with a minimum grade of "B-"
Explores the role of the immune system in cancer and the implications for the
host. The effect of the tumor-host interactions on the developing neoplasm
are studied by considering related topics such as angiogenesis, MMPs, chemokines
and metastasis. Additionally, the course explores the role of the immune system
in defense against the tumors and the mechanism by which cancer cells escape
the surveillance system.
RNA Biology and Diseases (PCB 6525) 3 credits
Prerequisite: Permission of instructor
Course provides advanced-level training in molecular biology of RNA. Topics
covered include principles of RNA structure, function and metabolism; methodologies
for studying RNA; diseases related to RNA deficiencies; and applications of
RNA technologies in research and clinical development.
Molecular Biology of the Cardiovascular
System and Cardiac Disease (PCB 6705) 3 credits
Prerequisites: BCH 3034, PCB 4023, or permission
of instructor
Examination of the molecular biology of cellular function focused on tissue
adaptation in cardiovascular disease. Investigation of survival responses to
cellular stress in atherosclerosis, cardiac hypertrophy, myocardial ischemia
and hypertension.
Reproductive Endocrinology (PCB 6804) 3
credits
Prerequisites: Permission of instructor
Course describes the origin, structure, properties and physiological actions
of hormones related to reproductive function, as well as the clinical implications
of their deficiency and excess at different stages of life. Anatomy, histology
and physiology of reproductive organs and related endocrine glands are studied.
This course is taught in a case-based manner. Students are required to prepare
and present a topic related to the lectures at the end of the course.
Adult Neurogenesis (PCB 6848) 3 credits
Prerequisites: Graduate standing and PSB 6037
or PSB 6345 or equivalent
The background of stem cells and neuroscience is covered followed by several
aspects of neurogenesis, including where neurogenesis happens in the brain,
how it happens, why it happens and, more importantly, how it might help the
brain heal itself.

Physiology of the Heart (PCB 6885) 3 credits
Prerequisites: BCH 3034, PCB 4023, or
permission of instructor
Course emphasizes the relationship between the biochemical properties of the
individual constituents of the heart cell (myocardium), the biophysics of cardiac
muscle function and the performance of the intact heart. The course format
will involve lectures, journal club presentations, round table discussions,
invited speakers as well as special projects.
Directed Independent Study (PCB 6905) 1-3
credits
Prerequisite: Permission of instructor
and department
Independent research.
Special Topics (PCB 6933) 1-8 credits
Prerequisite: Permission of instructor
Topics of interest to students in Biomedical Science, such as clinical microbiology
and protein misfolding and disease.
Graduate Seminars (PCB 6934) 1-2 credits
Graduate students will give one to two presentations on research papers or
specific topics (1-2 credits). Grading: S/U
Master’s Thesis (PCB 6971) 1-12 credits
Grading: S/U
Thesis-Related Research (PCB 6974) 2-3 credits
Prerequisite: Biomedical Science master’s
thesis students only
This course is a vehicle allowing students to conduct research for their master’s
thesis prior to writing and defending their proposal.
Developmental Neurobiology (PSB 6515) 3
credits
Prerequisites: PSY 1012 and PSB 3002
In-depth coverage of the principles and recent advances in the development
of the brain and nervous system, including nerve cell migration, axon outgrowth,
specificity, plasticity, neurotrophism, nerve cell death and the influence
of experience on the nervous system.

Link to
Charles E. Schmidt College of Medicine Programs
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